Publications

  1. CHRNA5 risk variant predicts earlier age at lung cancer diagnosis and delayed smoking cessation- a meta-analysis. Chen LS, Hung RJ, Baker T, Horton A, Culverhouse R, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kim C, Lutz S, Rosenberger A, Aben KK, Chang SC, Dieffenbach AK, Dienemann H, Brittni Fredericksen H, Han J, Pande M, Wrensch MR, McLaughlin J, Skaug V, van der Heijden HF, Wamplfer J, Wenzlaff A, Woll P, Zienolddiny S, Bickeböller H, Brenner H, Haugen A, Heinrich J, Hokanson J, Hunter D, Kiemeney LA, Le Marchand L, Liu G, Mayordomo J, Risch A. Schwartz A, Teare D, Wu X, Wiencke JK, Yang P, Zhang ZF, Spitz M, Kraft P, Amos CI, Bierut LJ.. JNCI, 14;107(5), 2014

  2. Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer. Poirier JG, Brennan P, McKay JD, Spitz MR, Bickeböller H, Risch A, Liu G, Le Marchand L, Tworoger S, McLaughlin J, Rosenberger A, Heinrich J, Brüske I, Muley, Henderson BE, Wilkens LR, Zong X, Li Y, Hao K, Timens W, Bossé Y, Sin DD, Obeidat M, Amos CI, Hung RJ. Genetic Epidemiology, 2015, 39(3):197-206

  3. Cannabis smoking and lung cancer risk: pooled analysis in the International Lung Cancer Consortium. Zhang LR, Morgenstern H, Greenland S, Chang SC, Lazarus P, Teare MD, Woll PJ, Orlow I, Cox B, Brhane Y, Liu G, Hung RJ. International Journal of Cancer, 2015 136(4):894- 903

  4. Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Wang Y, McKay JD, Rafnar T, Wang Z, Timofeeva MN, Broderick P, Zong X, Laplana M, Wei Y, Han Y, Lloyd A, Delahaye-Sourdeix M, Chubb D, Gaborieau V, Wheeler W, Chatterjee N, Thorleifsson G, Sulem P, Liu G, Kaaks R, Henrion M, Kinnersley B, Vallée M, LeCalvez-Kelm F, Stevens VL, Gapstur SM, Chen WV, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Krokan HE, Gabrielsen ME, Skorpen F, Vatten L, Njølstad I, Chen C, Goodman G, Benhamou S, Vooder T, Välk K, Nelis M, Metspalu A, Lener M, Lubinski J, Johansson M, Vineis P, Agudo A, Clavel-Chapelon F, Bueno-de-Mesquita HB, Trichopoulos D, Khaw KT, Johansson M, Weiderpass E, Tjønneland A, Riboli E, Lathrop M, Scelo G, Albanes D, Caporaso NE, Ye Y, Gu J, Wu X, Spitz MR, Dienemann H, Rosenberger A, Su L, Matakidou A, Eisen T, Stefansson K, Risch A, Chanock SJ, Christiani DC, Hung RJ, Brennan P, Landi MT, Houlston RS, Amos CI. Nat Genet. 2014 Jul;46(7):736-41

  5. A review of the application of inflammatory biomarkers in epidemiologic cancer research. Brenner DR, Scherer D, Muir K, Schildkraut J, Boffetta P, Spitz M, LeMarchand L, Chan AT, Goode EL, Ulrich CM, Hung RJCEBP, 23(9):1729-1751. 2014

  6. Exposure to secondhand tobacco smoke and lung cancer by histological subtype: a pooled analysis of the International Lung Cancer Consortium (ILCCO). Kim CH, Lee YC, Hung RJ, McNallan SR, Cote ML, Lim WY, Chang SC, Kim JH, Ugolini D, Chen Y, Liloglou T, Andrew AS, Onega T, Duell EJ, Field JK, Lazarus P, Marchand LL, Neri M, Vineis P, Kiyohara C, Hong YC, Morgenstern H, Matsuo K, Tajima K, Christiani DC, McLaughlin JR, Bencko V, Holcatova I, Boffetta P, Brennan P, Fabianova E, Foretova L, Janout V, Lissowska J, Mates D, Rudnai P, Szeszenia-Dabrowska N, Mukeria A, Zaridze D, Seow A, Schwartz AG, Yang P, Zhang ZF. IJC, 2014, 135(8):1918-30.

  7. Education and lung cancer among never smokers. Epidemiology. Menvielle G, Truong T, Jellouli F, Stücker I, Brenner H, Field JK, Hosgood HD, Lan Q, Landi MT, Hung RJ, Lazarus P, McLaughlin J, Morgenstern H, Muscat JE, Ruano-Ravina A, Schwartz AG, Seow A, Spitz MR, Tardon A, Zhang ZF, Luce D. 2014 Nov;25(6):934-5

  8. Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: The PAGE and TRICL consortia. Park SL, Fesinmeyer MD, Timofeeva M, Caberto C, Kocarnik JM, Han Y, Love S, Young A, Dumitrescu L, Lin Y, Wilkens LR, Matise T, Hindorff L, Fowke JH, Carty C, Buyske S, Schumacher FR, Butler A, Deelman E, Cote M, Rafnar T, Christiani DC, Field JK, Bickeboller H, Risch A, Heinrich J, Brennan P, Houlston R, Thun M, Albanes D, Caporaso N, Peters U, North KE, Heiss G, Crawford D, Bush WS, Haiman CA, Landi MT, Hung RJ, Kooperberg C, Amos CI, for the TRICL Research Team, Le Marchand L, Cheng I. JNCI paper, 2014 106(4):dju06

  9. Hormone use and risk for lung cancer: a pooled analysis from the International Lung Cancer Consortium (ILCCO). Pesatori AC, Carugno M, Consonni D, Hung RJ, Papadoupolos A, Landi MT, Brenner H, Müller H, Harris C, Duell E, Andrew A, McLaughlin J, Schwartz AG, Wenzlaff A, and Stucker I. British Journal of Cancer, 2013, 109(7):1954-64.

  10. Empirical Hierarchical Bayes Approach to Gene-Environment Interactions: Development and Application to Genome-Wide Association Studies of Lung Cancer in TRICL. Sohns M, Viktorova E, Amos CI, Brennan P, Fehringer G, Gaborieau V, Han Y, Heinrich J, Chang-Claude J, Hung RJ, Müller-Nurasyid M, Risch A, Lewinger JB, Thomas DC, Bickeböller H. Genetic Epidemiology, 2013, 37(6):551-9

  11. Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Brenner DR, Brennan P, Boffetta P, Amos C, Spitz M, Chen C, Goodman G, Wichmann E, Bickeboller H, Risch A, McLaughlin JR, Benhamou S, Lewinger JP, Witte JS, Chen G, Bull S, Hung RJ. Human Genetics, 132(5):579-89, 2013.

  12. Comparison of pathway analysis approaches using lung cancer GWAS data sets. Fehringer G, Liu G, Briollais L, Brennan P, Amos CI, Spitz MR, Bickeböller H, Wichmann HE, Risch A. Hung RJ. PLoS ONE, 2012, 2012;7(2):e31816.

  13. Previous lung disease and lung cancer risk: a pooled analysis from the international lung cancer consortium. Brenner DR, Boffetta P, Duell EJ, Bickeböller H, Rosenberger A, McCormack V, Muscat JE, Yang P, Wichmann HE, Brueske-Hohlfeld I, Schwartz AG, Cote ML, Tjønneland A, Friis S, Le Marchand L, Zhang ZF, Morgenstern H, Szeszenia-Dabrowska N, Lissowska J, Zaridze D, Rudnai P, Fabianova E, Foretova L, Janout V, Bencko V, Schejbalova M, Brennan P, Mates IN, Lazarus P, Field JK, Raji O, McLaughlin JR, Liu G, Wiencke J, Neri M, Ugolini D, Andrew AS, Lan Q, Hu W, Orlow I, Park BJ, Hung RJ. AJE, 2012 176 (7): 573-85

  14. Influence of Common Genetic Variation on Lung Cancer Risk: Meta-Analysis of 14,900 Cases and 29,485 Controls. Timofeeva MN, Hung RJ, Rafnar T, Christiani DC, Field JK, Bickeboller H, Risch A, McKay JD, Wang Y, Dai J, Gaborieau V, McLaughlin J, Brenner D, Narod S, Caporaso NE, Albanes D, Thun M, Eisen T, Wichmann HE, Rosenberger A, Han Y, Chen W, Zhu D, Spitz M, Wu X, Pande M, Zhao Y, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Krokan HE, Gabrielsen ME, Skorpen F, Vatten L, Njølstad I, Chen C, Goodman G, Lathrop M, Benhamou S, Vooder T, Välk K, Nelis M, Metspalu A, Raji O, Chen Y, Gosney J, Liloglou T, Muley T, Dienemann H, Thorleifsson G, Shen H, Stefansson K, Brennan P, Amos CI, Houlston R, Landi MT; for TRICL Research Team. Human Molecular Genetics, 21(22):4980-95. 2012

  15. Natural and Orthogonal Interaction Framework for Modeling Gene-Environment Interactions with Application to Lung Cancer. Ma J, Xiao F, Xiong M, Andrew AS, Brenner H, Duell EJ, Haugen A, Hoggart C, Hung RJ, Lazarus P, Liu C, Matsuo K, Mayordomo JI, Schwartz AG, Staratschek-Jox A, Wichmann E, Yang P, Amos CI. Hum Hered. 2012 Aug 9;73(4):185-194.

  16. Asthma and Lung Cancer Risk: A Systematic Investigation by the International Lung Cancer Consortium. Rosenberger A, Bickeböller H, McCormack V, Brenner DR, Duell EJ, Tjønneland A, Friis S, Muscat JE, Yang P, Wichmann HE, Heinrich J, Szeszenia-Dabrowska N, Lissowska J, Zaridze D, Rudnai P, Fabianova E, Janout V, Bencko V, Brennan P, Mates D, Schwartz AG, Cote ML, Zhang ZF, Morgenstern H, Oh SS, Field JK, Raji O, McLaughlin JR, Wiencke J, Lemarchand L, Neri M, Bonassi S, Andrew AS, Lan Q, Hu W, Orlow I, Park BJ, Boffetta P, Hung RJ. Carcinogenesis 2012,33(3):587-97.

  17. Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium. Cote ML, Liu M, Bonassi S, Neri M, Schwartz AG, Christiani DC, Spitz MR, Muscat JE, Rennert G, Andrew AS, Bencko V, Bickeböller H, Boffetta P, Brennan P, Brenner H, Duell EJ, Fabianova E, Field JK, Foretova L, Friis S, Harris CC, Holcatova I, Hong YC, Isla D, Janout V, Kiemeney LA, Kiyohara C, Lan Q, Lazarus P, Lissowska J, Le Marchand L, Mates D, Matsuo K, I. Mayordomo JI, McLaughlin JR, Morgenstern H, Müller H, Orlow I , Park BJ, Raji OY, Rudnai P, Seow A, Stucker I, Szeszenia-Dabrowska N, Teare MD, Tjønnelan A, Ugolini D, van der Heijden HFM, Wichmann E, Wiencke JK, Woll PJ, Yang P, Zaridze D, Zhang ZF, Etzel CJ, Hung RJ. European Journal of Cancer, 2012 in press.

  18. International Lung Cancer Consortium: Pooled Analysis of Previous Lung Diseases and Lung Cancer Risk. Brenner DR, Boffetta, P, Duell, EJ, Bickeböller, H, Rosenberger A, Muscat, JE,Yang, P, Wichmann, E, Schwartz, AG, Tjønneland, A, Friis, S, LeMarchand, L, Zhang, ZF, Lazarus, P, Field, J, McLaughlin, J, Wiencke, J, Neri, M, Lan, Q, Orlow, I, Park, BJ, Hung RJ. AJE, 2012 in press

  19. Lung cancer and DNA repair genes: Multilevel association n analysis from the International Lung Cancer Consortium. Kazma R, Babron MC, Gaborieau V, Génin E, Brennan P, Hung RJ, McLaughlin JR, Krokan HE, Elvestad MB, Skorpen F, Anderssen E, Vooder T, Välk K, Metspalu A, Field JK, Lathrop M, Sarasin A, Benhamou S; for the ILCCO consortium. Carcinogenesis, 2012, 33(5):1059-1064.

  20. Aspirin and NSAID use and lung cancer risk: a pooled analysis in the International Lung Cancer Consortium (ILCCO). McCormack V, Hung RJ, Brenner DR, Bickeböller H, Rosenberger A, Muscat JE, Lazarus P, Tjønneland A, Friis S, Christiani DC, Chun E, Le Marchand L, Rennert G, Rennert HS, Andrew AS, Orlow I, Park P, Boffetta P, Duell EJ. Cancer Causes and Controls, 2011, 22(12):1709-20.

  21. Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case-control studies in the International Lung Cancer Consortium (ILCCO). Boffetta B, Jayaprakash V, Yang P, Asomaning K, Muscat JE, Schwartz AG, Zhang ZF, Le Marchand L, Cote ML, Stoddard SM, Morgenstern H, Hung RJ, Christiani DC. Cancer Causes and Controls, 2010. 22(1):73-9

  22. In-home coal and wood use and lung cancer risk: a pooled-analysis of the International Lung Cancer Consortium. Hosgood HD, Boffetta P, Greenland S, Lee YCA, McLaughlin J, Seow A, Duell EJ, Andrew AS, Zaridze D, Szeszenia-Dabrowska N, Rudnai P, Lissowska J, Fabiánová E, Mates D, Bencko V, Foretova L, Janout V, Morgenstern H, Rothman N, Hung RJ, Brennan P, Lan Q. Environment Health Perspective, 118(12):1743-7

  23. International Lung Cancer Consortium: Replication of susceptibility loci on chromosome 15q25, 5p15 and 6p21. Thérèse Truong, Rayjean J Hung, Christopher I Amos, Xifeng Wu, Heike Bickeböller, Albert Rosenberger, Wiebke Sauter, Thomas Illig6, H.-Erich Wichmann, Angela Risch, Hendrik Dienemann, Rudolph Kaaks, Ping Yang, Ruoxiang Jiang, John K Wiencke, Margaret Wrensch, Helen Hansen, Karl T Kelsey, Keitaro Matsuo, Kazuo Tajima, Ann G. Schwartz, Angie Wenzlaff, Adeline Seow, Chen Ying, Andrea Staratschek-Jox, Peter Nürnberg, Erich Stoelben, Jürgen Wolf, Philip Lazarus, Joshua E Muscat, Carla Gallagher, Shanbeh Zienolddiny, Aage Haugen, Henricus FM van der Heijden, Lambertus A. Kiemeney, Dolores Isla, Jose Ignacio Mayordomo, Thorunn Rafnar, Kari Stefansson, Zuo-Feng Zhang, Shen-Chih Chang, Jin Hee Kim, Yun-Chul Hong, Eric J Duell, Angeline S Andrew, Flavio Lejbkowicz, Gad Rennert, Heiko Müller, Herman Brenner, Loïc Le Marchand, Simone Benhamou, Christine Bouchardy, M Dawn Teare, Xiaoyan Xue, John McLaughlin, Geoffrey Liu, James D McKay, Paul Brennan, Margaret Spitz. JNCI 102(13):959-71, 2010

  24. International Lung Cancer Consortium: Coordinated association study of 10 potential lung cancer susceptibility variants. Therese Truong, Wiebke Sauter, James D. McKay, H. Dean Hosgood III, Carla Gallagher , Christopher I. Amos, Margaret Spitz, Joshua Muscat, Philip Lazarus, Thomas Illig, H. Erich Wichmann , Heike Bickeboeller, Angela Risch, Hendrik Dienemann, Zuo-Feng Zhang, Behnaz Pezeshki Naeim, Ping Yang, Shanbeh Zienolddiny, Aage Haugen, Loïc Le Marchand, Yun-Chul Hong, Jin Hee Kim, Eric J. Duell, Angeline S. Andrew, Chikako Kiyohara, Hongbing Shen, Keitaro Matsuo, Takeshi Suzuki, Adeline Seow, Daniel PK Ng, Qing Lan, David Zaridze, Neonilia Szeszenia-Dabrowska , Jolanta Lissowska, Peter Rudnai, Eleonora Fabianova, Vali Constantinescu , Vladimir Bencko, Lenka Foretova, Vladimir Janout, Amélie Chabrier, Paolo Boffetta, Paul Brennan and Rayjean J Hung. Carcinogenesis, 2010 Apr;31(4):625-33

  25. International Lung Cancer Consortium: Pooled analysis of Sequence Variants in DNA Repair and Cell Cycle Control Pathways. Hung RJ, Christiani DC, Risch A, Popanda O, Haugen A, Zienolddiny S, Benhamou S, Bouchardy C, Lan Q, Spitz MR, Wichmann H-E, Le Marchand L, Vineis P, Matullo G, Kiyohara C, Zhang Z-F, Pezeshki B, Harris C, Mechanic L, Seow A, Ng D.P.K., Szeszenia-Dabrowska N, Zaridze D, Lissowska J, Rudnai P, Fabianova E, Mate D, Foretova L, Janout V, Bencko V, Caporaso N, Chen C, Duell EJ, Goodman G, Field JK, Houlston RS, Hong Y-C , Landi MT, Lazarus P, Muscat J, McLaughlin J, Schwartz AG , Shen H, Stucker I, Tajima K, Matsuo K, Thun KM, Yang P, Wiencke J, Andrew AS, Monnier S, Boffetta P, Brennan P. CEBP 2008, Cancer Epi.Biomarker Prev. , 2008 Nov;17(11):3081-9.

  26. Genetic polymorphisms in base excision repair pathways and cancer risk: a HuGE disease association review. Hung RJ, Hall J, Brennan P, Boffetta P. American J. Epidemiology 2005. 162 (10):p25-42.